HUMAN PLASMABLAST MIGRATION TOWARD CXCL12 REQUIRES GLUCOSE OXIDATION BY ENHANCED PYRUVATE DEHYDROGENASE ACTIVITY VIA AKT

Human Plasmablast Migration Toward CXCL12 Requires Glucose Oxidation by Enhanced Pyruvate Dehydrogenase Activity via AKT

Migration of human plasmablast to the bone marrow is essential for the final differentiation of plasma cells and maintenance of effective humoral immunity.This migration is controlled by CXCL12/CXCR4-mediated activation of the protein kinase AKT.Herein, we show that the CXCL12-induced migration of human plasmablasts is dependent on glucose oxidatio

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The Alignment of INTOSAI and Romanian Public External Audit Standards, Guidelines and Institutional Focus to the Data Driven Context

Disruptive technologies are shaping our world in a wide range of manners, from targeted advertising to self-driving cars.Their impact becomes more complex in BOSCH Serie 4 KGN39VL35G 60/40 Fridge Freezer - Silver highly-regulated, judgmentintensive fields, such as public external audit.While auditees operate in an increasingly dataintensive environ

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Short sleep duration is associated with shorter telomere length in healthy men: findings from the Whitehall II cohort study.

Shorter telomere length and poor sleep are more prevalent at older ages, but their relationship is uncertain.This study explored associations between sleep duration and telomere length in a sample of healthy middle and early old age people.Participants were 434 men and women aged 63.3 years on average drawn from the Whitehall Universal Simmerstat I

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